A Rare Case of Pleural Effusion Burkitt’s Lymphoma with Tumor Lysis Syndrome in an HIV, HHV8, EBV, and HCV Negative Young Male Patient
نویسنده
چکیده
We report an unusual case of a 25 year-old male with Burkitt’s like disease associated with Primary Effusion Lymphoma (PEL), who was negative for HIV, HHV8, HCV, and EBV. The pleural effusion contained lymphoma cells with B-cell lineage and c-myc gene rearrangement. The patient had a rapidly progressive and fatal course and died from tumor lysis syndrome. This is the second reported case in the literature of such unique characteristics. Further understanding of the molecular and pathogenetic mechanisms underlying this disease is warranted.
منابع مشابه
Aggressive and Hiv-negative Hhv8-unrelated Primary Effusion-like Lymphoma with T-cell Phenotype: a Rare Case Report
Introduction: Primary effusion lymphoma (PEL) is a rare type of non-Hodgkin’s lymphoma, which is characterized by serous effusion in body cavities without detectable tumor masses or lymphadenopathy. It is usually found in human herpes virus 8 (HHV8) and human immunodeficiency virus (HIV) positive patients, and tumor cells usually show a B-cell–lineage immunophenotype. Case presentation: In the ...
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